A numerical approach for the stress concentration of periodic collinear holes in an infinite plate in tension is presented. It involves the fictitious stress method and a generalization of Bueckner's principle. Numerical examples are concluded to show that the numerical approach is very efficient and accurate for analyzing the stress concentration of periodic collinear holes in an infinite plate in tension. The stress concentration of periodic collinear square holes in an infinite plate in tension is studied in detail by using the numerical approach. The calculated stress concentration factor is proven to be accurate.