With centrally loaded charges, the deformation of the cylindrical vessel is concentrated in the range of L/R = ±2 by the blast center. The reactive reinforcement method, which uses dispersive charges cooperating with vessels to control the concentrated charge, is presented in this study. The experimental research on this reactive reinforcement method is tested experimentally. Global and flakelike charges are selected as the inner and outer charges, respectively. This method primarily focuses on synchronizations, especially the detonation synchronization of such inner and outer charges. A detonation system is designed, and central and multipoint detonation techniques are used to control the synchronization. Three experiments are performed, of which two are advanced studies. The third is an experimental research on the method. Results show that the max time difference of the detonation system is 1 μs, suggesting good synchronization performance. The strain of the vessel is reduced by about 71.4% using the reinforcement method. This study provides a reference for the reinforcement method in practical applications.